MRSA Research Today is a free monthly online journal that collates and summarizes the latest research about MRSA, including details on methicillin-resistant staphylococcus aureus, hospitals, infection, antibiotic resistance, superbugs.

Inhibition of Dermal MRSA Colonization by Microalgal Micro- and Nanoparticles.

Lukowski G, Lindequist U, Mundt S, Kramer A, Jülich WD

Institute of Marine Biotechnology e.V. and Institutes, Ernst Moritz Arndt University Greifswald, Greifswald, Germany.

The aim of this study was to investigate the prevention of the dermal colonization of methicillin-resistant Staphylococcus aureus (MRSA) strains by the application of micro- and nanoparticles called Maresometrade mark. Maresometrade mark were prepared from selected microalgae by a novel emulsion technique. They contain lipids and all other components of the microalgae in an encapsulated form. It could be shown that Maresometrade mark prepared from a cyanobacterial strain of the order Nostocales (Bio33-Maresometrade mark) were able to inhibit the dermal colonization of different MRSA strains (North German Epidemic Strain, Col, N315) and even of the vancomycin-resistant strain MU50 in the models 'mouse ear' and 'cow udder teat'. Pretreatment of the skin with Maresometrade mark reduced the number of attached MRSA by 3-4 log units in comparison to the control. We assume that a prophylactic skin care with Maresometrade mark could complete the multibarrier anti-infectious strategy against MRSA. Copyright (c) 2008 S. Karger AG, Basel.

Published 16 January 2008 in Skin Pharmacol Physiol, 21(2): 98-105.
Full-text of this article is available online (may require subscription).

© 2004-2008 MRSA Research Today. All Rights Reserved.